Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptide
FADD
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN976567
Quick Overview for Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptide (ABIN976567)
Target
FADD
(Fas (TNFRSF6)-Associated Via Death Domain (FADD))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Fadd antibody (Catalog #: ARP30294_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Background
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Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Alias Symbols: Mort1/FADD
Protein Interaction Partner: Nol3
Protein Size: 205 -
Molecular Weight
- 23 kDa
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Gene ID
- 14082
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NCBI Accession
- NM_010175, NP_034305
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UniProt
- Q61160
Target
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